Osteogenesis imperfecta (OI) is a genetic or heritable disease in which bones fracture (break) easily, often with no obvious cause or minimal injury. OI is also known as brittle bone disease, and the symptoms can range from mild with only a few fractures to severe with many medical complications. In Vietnamese, oi, spelt in the Vietnamese alphabet as ơi, is regularly used to call attention to a person in a sentence. It is used in conjunction with a name or a pronoun. Osteogenesis imperfecta (brittle bone disease) is a genetic disease that makes your bones thin and brittle. People with osteogenesis imperfecta break bones easily, with little or no force causing the break. O-I Glass is a leading glass bottle manufacturer, designing innovative glass packaging for the world's leading brands. We love infinitely recyclable, healthy, sustainable glass packaging. Osteogenesis imperfecta (OI), also known as brittle bone disease, is an inherited disorder of the connective tissue. A child born with OI may have soft bones that fracture easily, bones that are not formed normally, and other problems. The mission of the OI Foundation is to improve the quality of life for those living with osteogenesis imperfecta through research, education, awareness and mutual support. Learn when to spell /oi/ or /oy/ with a singing yeti. Go to Nessy.com for free, printable worksheets and card games!.more Play free IO games online at Poki. Battle, race, survive, and team up in fast-paced multiplayer arenas, all instantly playable in your browser. Osteogenesis imperfecta (OI), sometimes called “brittle bone disease, is a form of skeletal dysplasia. It is a congenital disorder in which a person is born with very weak bones, which leads to frequent fractures and other health problems. Osteogenesis imperfecta (OI) is a group of genetic disorders that mainly affect the bones. Explore symptoms, inheritance, genetics of this condition.